Fast Detection of Prostate Malignant Tissue by Multipulsed Laser-Induced Breakdown Spectroscopy (LIBS)

  • A. Ponce Onteko LLC, 9924 Alexanders Ridge Dr., Olive Branch, MS 38654, USA
  • T. Flores Onteko LLC, 9924 Alexanders Ridge Dr., Olive Branch, MS 38654, USA
  • L. Ponce Saint Petersburg Electrotechnical University, Professora Popova St 5, 197376 St. Petersburg, Russia

Abstract

 In this work, we evaluated the use of laser-induced breakdown spectroscopy (LIBS) coupled with chemometric methods as a fast and simple technique for identifying diseased tissue in prostate cancer samples. The experimental setup consisted of a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser in a burst-mode regime, with differing time delays for the spectrometer readings. To improve classification accuracy, principal component analysis (PCA) was coupled with neural analysis (NA), achieving a high identification accuracy of 97%. It can be concluded that LIBS has the potential to serve as a technique for the detection and diagnosis of human prostate cancer.


 

Published
Dec 14, 2022
How to Cite
PONCE, A.; FLORES, T.; PONCE, L.. Fast Detection of Prostate Malignant Tissue by Multipulsed Laser-Induced Breakdown Spectroscopy (LIBS). Revista Cubana de Física, [S.l.], v. 39, n. 2, p. 81-84, dec. 2022. ISSN 2224-7939. Available at: <https://revistacubanadefisica.org/index.php/rcf/article/view/2022v39p081>. Date accessed: 08 feb. 2023.
Section
Original Articles